To cater to the needs of open-heart surgeries and other operations, Sevabharathi Tamilnadu is motivating people to voluntarily donate blood in large numbers.  Door-to-door blood donation campaigns are arranged to create awareness among the masses.  In Tamilnadu, two blood banks and 26 blood donation centres are actively involved in this work.

Apart from this, small camps are arranged in many areas for blood-group testing and the participants are encouraged to contribute their blood to the needy. In the blood banks, the recipients of blood – i.e., the attendants and relatives of the patient – are also motivated to become regular blood donors. The blood provided to the patients is screened adequately for ensuring quality and is priced nominally to meet the screening expenses.